Endocrine Abstracts

Even in the presence of normally circulating androgens, the imbalance between estrogen and androgen in males between the prepubertal and pubertal periods may have an impact on male reproductive function. While there are many variables that affect how each person reaches puberty at different times, boys who are becoming more obese have higher aromatase activity. This enzyme turns testosterone into estradiol permanently, which lowers testosterone levels and raises estrogen level...

Overview: Numerous epidemiological studies have demonstrated that low testosterone levels are linked to poor life quality and sexual quality, and that hypoestrogenic hypogonadism in obese male patients is connected with and predicts the development of metabolic syndrome and type 2 diabetes in the future. The purpose of the study was to demonstrate how aromatase inhibitors affected anthropometric traits, HOMA-IR, blood pressure, glycosylated hemoglobin level, and dyslipidemia i...